WHILE THE CONVENTIONAL ROLE FOR P53 IS TO ACT AS A TUMOR SUPPRESSOR BY SENSING DNA DAMAGE AND INDUCING CELL CYCLE ARREST AND CELL APOPTOSIS, THE POSSIBILITY SHOULD NOT BE RULED OUT THAT METFORMIN MAY INDUCE ATM CHK2 S AND ATM P53 S ABILITY TO PROMOTE WHILE THE CONVENTIONAL ROLE FOR P53 IS TO ACT AS A TUMOR SUPPRESSOR BY SENSING DNA DAMAGE AND INDUCING CELL CYCLE ARREST AND CELL APOPTOSIS, THE POSSIBILITY SHOULD NOT BE RULED OUT THAT METFORMIN MAY INDUCE ATM CHK2 S AND ATM P53 S ABILITY TO PROMOTE
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